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Best Practice & Research Clinical Haematology
Volume 22, Issue 3
, Pages 303-313
, September 2009
Treatment strategies for CML
References
- . The story of chronic myeloid leukaemia. Br J Haematol. 2000;110:2–11
- . Chronic granulocytic leukaemia: comparison of radiotherapy and busulphan therapy. Br Med J. 1968;(1):201–208
- Disappearance of Ph1 positive cells in four patients with chronic granulocytic leukemia after chemotherapy, irradiation and marrow transplantation from an identical twin. N Engl J Med. 1979;300:333–337
- Marrow transplantation for patients in the chronic phase of chronic granulocytic leukaemia. Lancet. 1982;(2):623–625
- Allogeneic bone marrow transplantation for chronic myelogenous leukaemia. Lancet. 1984;(1):665–668
- Hematologic remission and cytogenetic improvement induced by recombinant human interferon alpha A in chronic myelogenous leukemia. N Engl J Med. 1986;314:1065–1069
- . Interferon alfa-2a as compared with conventional chemotherapy for the treatment of chronic myeloid leukemia. N Engl J. Med. 1994;330:820–825
- Interferon alfa-2b combined with cytarabine versus interferon alone in chronic myelogenous leukemia. French Chronic Myeloid Leukemia Study Group. N Engl J Med. 1997;337:223–229
- Chronic myeloid leukemia and interferon-alfa: a study of complete cytogenetic responders. Blood. 2001;98:3074–3081
- Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med. 2001;344:1031–1037
- Imatinib compared with interferon and low- dose Ara-C for newly diagnosed chronic phase chronic myeloid leukemia. N Engl J Med. 2003;348:994–1004
- Five-year follow-up of imatinib therapy for chronic-phase chronic myeloid leukemia. N Engl J Med. 2006;355:2408–2417
- International Randomized Study of Interferon versus STI571 (IRIS) 7-year follow-up: sustained survival, low rate of transformation and increased rate of major molecular response (MMR) in patients (pts) with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib (IM). Blood. 2008;112:76;[Abstract #186]
- Six year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia. Leukemia. 2009;213:1054–1061
- Imatinib for newly diagnosed patients with chronic myeloid leukemia in chronic phase: incidence of sustained responses in an intention to treat analysis. J Clin Oncol. 2008;26:3358–3363
- High dose imatinib mesylate therapy in newly diagnosed philadelphia chromosome-positive chronic myeloid leukemia. Blood. 2004;103:2873–2878
- Imatinib (IM) pharmacokinetics (PK) exposure and its correlation with clinical outcome in patients with chronic-phase chronic myeloid leukemia (CML-CP) for 400
mg and 800 mg daily doses (tyrosine kinase dose optimization study [TOPS]). Blood. 2008;112:170;[abstr 447] - Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med. 2006;12:908–916
- The use of imatinib (STI571) in chronic myeloid leukemia: some practical considerations. Haematologica. 2002;87:980–989
- Practical management of patients with chronic myeloid leukemia receiving imatinib. J Clin Oncol. 2003;21:1637–1647
- Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia. N Engl J Med. 2003;349:1423–1432
- Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than two years. Blood. 2007;109:58–60
- Is it possible to stop imatinib in patients with chronic myeloid leukemia? An update from the French pilot study and first results of the multicentre ‘Stop Imatinib (STIM) study. Blood. 2008;112:76;[Abstract #187]
- Evolving concepts in the management of chronic myeloid leukemia. recommendations from an expert panel on behalf of the European leukemiaNet. Blood. 2006;108:1809–1820
- Baccarani M, Cortes J, Pane F, et al. Chronic myeloid leukemia: an update of concepts and management recommendations of the European LeukemiaNet. J Clin Ocol, in press, doi:10.1200/JCO.2009.25.0779.
- Transient benefit only from increasing imatinib dose in CML patients who do not achieve complete cytogenetic remissions on conventional doses. Blood. 2003;102:2702–2703
- Imatinib mesylate dose escalation with durable responses in patients with chronic myeloid leukemia after cytogenetic failure on standard-dose imatinib therapy. Blood. 2009;113:2154–2160
- Failure to achieve a major cytogenetic response by twelve months defines inadequate response in patients receiving nilotinib or dasatinib as second or subsequent line therapy for chronic myeloid leukemia. Blood. 2008;112:516–518
- Milojkovic D, Nicholson M, Apperley JF, et al. Early prediction of success or failure using second-generation tyrosine kinase inhibitors for chronic myeloid leukemia. Haematologica, in press.
- . Chronic myeloid leukemia: current treatment options. Blood. 2001;98:2039–2042
- Allogeneic hematopoietic stem cell transplantation for chronic myeloid leukemia in Europe 2006: transplant activity, long-term data and current results. Chronic leukemia working party of the European Group for Blood and Marrow Transplantation. Haematologica. 2006;91:513–521
- . Innovative approaches of targeted therapy for CML of childhood in combination with paediatric haematopoietic SCT. Bone Marrow Transplant. 2008;42(Suppl. 2):S40–S46
- Garg RJ, Kantarjian HM, O'Brien S, et al. The use of nilotinib or dasatinib after failure of two prior tyrosine kinase inhibitors (TKI): long-term follow-up. Blood, in press, doi:10.1182/blood-2009-05-221531.
- Randomized comparison of imatinib versus imatinib combination therapies in newly diagnosed chronic myeloid leukemia (CML) patients in chronic phase (CP): first results of the Phase III (SPIRIT) trial from the French CML Group (FI LMC). [Abstract #183] Blood. 2008;112:74
- Efficacy of nilotinib (formerly AMN107) in patients with newly diagnosed previously untreated Philadelphia chromosome (Ph)-positive chronic myelogenous leukemia in early chronic phase. Blood (ASH Annual Meeting Abstracts). 2008;112:[Abstract #446]
- Dasatinib (SPRYCEL) in patients with previously untreated chronic myelogenous leukemia (CML) in early chronic phase (CML-CP). Blood (ASH Annual Meeting Abstracts). 2006;112:[Abstract #2161]
- Goldman JM, Majhail NS, Klein J, et al. Myeloablative allogeneic hematopoietic cell transplantation for chronic myeloid leukemia in first chronic phase: incidence of relapse and late mortality in 5-year survivors, submitted for publication.
- Primitive, quiescent Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro. Blood. 2002;99:319–325
- Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction. Blood. 2006;107:4532–4539
- Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med. 2004;351:657–667
- BMS-214662 potently induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitors. Blood. 2008;111:2843–2855
- . Treatment of philadelphia chromosome-positive acute lymphoblastic leukemia. Hematology Am Soc Hematol Educ Program. 2005;118–122
- . Philadelphia chromosome positive acute lymphocytic leukemia: a new era of challenges. Hematology Am Soc Hematol Educ Program. 2007;435–443
PII: S1521-6926(09)00056-5
doi: 10.1016/j.beha.2009.08.001
© 2009 Elsevier Ltd. All rights reserved.
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Best Practice & Research Clinical Haematology
Volume 22, Issue 3
, Pages 303-313
, September 2009
