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Best Practice & Research Clinical Haematology
Volume 21, Issue 3
, Pages 391-404
, September 2008
Peptide vaccines for myeloid leukaemias
References
- . T-cell immunotherapy of tumours by adoptive transfer of cytotoxic T lymphocytes and by vaccination with minimal essential epitopes. Immunological Reviews. 1995;145:167–177
- . Cytotoxic T-lymphocyte (CTL) responses against acute or chronic myeloid leukemia. Immunological Reviews. 1997;157:223–230
- . Graft-versus-leukemia: no longer an epiphenomenon. Blood. 1993;82:2273–2277
- . Non-myeloablative stem cell transplants. British Journal of Haematology. 2000;111:6–17
- Graft-versus-leukemia reactions in allogeneic chimera. Blood. 2004;103:767–776
- Relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: the case for giving donor lymphocyte transfusion before the onset of hematological relapse. Blood. 1994;83:3377–3383
- . Adoptive immunotherapy with donor lymphocyte transfusions. Current Opinion in Oncology. 1997;9:139–145
- Minor histocompatibility antigens in human stem cell transplantation. Experimental Hematology. 2003;31:734–751
- T cells recognizing leukemic CD34+progenitor cells mediate the anti-leukemic effect of donor lymphocyte infusions for relapsed chronic myeloid leukemia after allogeneic stem cell transplantation. Proceedings of the National Academy of Sciences of the United States of America. 1998;95:10152–10157
- BCR-ABL-specific T cells can be detected in healthy donors and in chronic myeloid leukemia patients following allogeneic stem cell transplantation. Blood. 2004;103:3245
- Use of leukemic dendritic cells for the generation of anti-leukemic cellular cytotoxicity against Philadelphia chromosome-positive chronic myelogenous leukemia. Blood. 1997;89:1133–1142
- . CML vaccines as a paradigm of the specific immunotherapy of cancer. Blood Reviews. 2000;14:111–120
- The DBY gene codes for an HLA-DQ5-restricted human male-specific minor histocompatibility antigen involved in graft-versus-host disease. Blood. 2002;99:3027–3032
- . Immunotherapeutic peptide vaccination with leukemia-associated antigens. Current Opinion in Immunology. 2006;18:599–604
- . Translational mini-review series on vaccines: peptide vaccines for myeloid leukemias. Clinical and Experimental Immunology. 2007;148:189–198
- DNA fusion vaccines induce epitope-specific cytotoxic CD8+ T cells against human leukemia-associated minor histocompatibility antigens. Cancer Research. 2006;66:5436
- . Immunotherapy of acute myeloid leukemia: development of a whole cell vaccine. Frontiers in Bioscience. 2008;13:2022–2029
- . Dendritic cell vaccines for leukemia patients. Expert Review of Anticancer Therapy. 2007;7:275–283
- Specific human cellular immunity to bcr-abl oncogene-derived peptides. Blood. 1996;87:3587–3592
- Targeted T-cell therapy for human leukemia: cytotoxic T lymphocytes specific for a peptide derived from proteinase 3 preferentially lyse human myeloid leukemia cells. Blood. 1996;88:2450–2457
- Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell. 1990;60:509–520
- WT1 peptide cancer vaccine for patients with hematopoietic malignancies and solid cancers. Science World Journal. 2007;7:649–665
- The receptor for hyaluronic acid-mediated motility induces specific CD8+ T cells response in healthy donors and patients with chronic myeloid leukemia after allogeneic stem cell transplantation. International Journal of Oncology. 2007;30:1119–1127
- Vaccination of patients with chronic myelogenous leukemia with bcr-abl oncogene breakpoint fusion peptides generate specific immune responses. Blood. 2000;95:1781–1787
- A multivalent bcr-abl fusion peptide vaccination trial in patients with chronic myeloid leukemia. Blood. 2004;103:1037–1042
- Clinical evaluation of BCR-ABL peptide immunization in chronic myeloid leukemia: results of the EPIC study. Leukemia. 2007;21:2287–2295
- Effect of p210 multipeptide vaccine associated with imatinib or interferon in patients with chronic myeloid leukemia and persistent residual disease: a multi center observation trial. The Lancet. 2005;365:657–662
- Complete remission in a patient with recurrent myeloid leukemia induced by vaccination with WT1 peptide in the absence of hematological or renal toxicity. Leukemia. 2004;18:165–166
- Clinical and immune responses of WT1-peptide vaccination in patients with acute myeloid leukemia. ASCO Annual Meeting Proceedings. Journal of Clinical Oncology. 2006;24:2511
- Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression. Proceedings of the National Academy of Sciences of the United States of America. 2004;101:13885–13890
- Clinical and immunologic responses to very low-dose vaccination with WT1 peptide (5 micrg/body) in a patient with chronic myelomonocytic leukemia. International Journal of Hematology. 2007;85:426–429
- Vaccination with the PR1 leukemia-associated antigen can induce complete remission in patients with myeloid leukemia. Blood. 2004;104:[abstract 259]
- RHAMM-R3 peptide vaccination in patients with acute myeloid leukemia, myelodysplastic syndrome, and multiple myeloma elicits immunologic and clinical responses. Blood. 2008;111:1357–1365
- Specific binding of leukemia oncogene fusion peptides to HLA class I molecules. Blood. 1995;85:2680–2684
- Two bcr-abl junction peptides bind HLA-A3 molecules and allo specific induction of human cytotoxic T lymphocytes. Leukemia. 1996;10:693–699
- Peptides derived from the whole sequences of BCR-ABL bind to several class I molecules allowing specific induction of human cytotoxic T lymphocytes. European Journal of Immunology. 1997;27:2066–2072
- Peptides spanning the junctional region of both the abl/bcr and the bcr/abl fusion proteins bind common HLA class I molecules. Leukemia. 2000;14:419–426
- Proteosomal degradation of BCR/ABL protein can generate an HLA-A*0301-restricted peptide, but high-avidity T cells recognizing this leukemia-specific antigen were not demonstrated. Haematologica. 2004;89:1062–1071
- Direct evidence that leukemic cells present HLA-associated immunogenic peptides derived from the BCR-ABL b3a2 fusion protein. Blood. 2001;98:2887–2893
- Cytotoxic T cell response against chimeric p210 BCR-ABL protein in patients with chronic myelogenous leukemia. The Journal of Clinical Investigation. 1998;101:2290–2296
- Synthetic peptide analogs derived from bcr/abl fusion protein and the induction of heteroclitic human T cell responses. Haematologica. 2005;90:1324–1332
- . In vivo induction of cytotoxic T cell response by a free synthetic peptide requires CD4+ T cell help. Journal of Immunology (Baltimore, Md.: 1950). 1991;147:4069–4073
- Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CD8+ CTL in vivo with peptide vaccine constructs. Journal of Immunology (Baltimore, Md.: 1950). 1994;152:549–556
- Helper T cell determinant peptide contributes to induction of cellular immune responses by peptide vaccines against hepatitis C virus. The Journal of General Virology. 1999;80:187–193
- T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature. 1998;393:480–483
- The optimization of helper T lymphocyte (HTL) function in vaccine development. Immunologic Research. 1998;18:79–92
- Effects of granulocyte-macrophage colony-stimulating factor and foreign helper protein as immunologic adjuvants on the T-cell response to vaccination with tyrosinase peptides. International Journal of Cancer. 2003;104:188–194
- Generation of NY-ESO-1-specific CD4+ and CD8+ T cells by a single peptide with dual MHC class I and II specificities: a new strategy for vaccine design. Cancer Research. 2002;62:3630–3635
- T-cell immunity to the joining region of p210 BCR-ABL protein. Proceedings of the National Academy of Sciences of the United States of America. 1992;89:1468–1472
- Graft-versus-leukemia in retrovirally induced murine CML model: mechanisms of T-cell killing. Blood. 2004;103:4353–4361
- HLA class II-restricted antigen presentation of endogenous bcr-abl fusion protein by chronic myelogenous leukemia-derived dendritic cells to CD4 (+) T lymphocytes. Blood. 2001;98:1498–1505
- Recognition of BCR-ABL positive leukemic blasts by human CD4+ T cells elicited by priming in vitro immunization with a BCR-ABL breakpoint peptide. Blood. 1996;88:3522–3527
- A BCR-ABL oncoprotein p210 b2a2 fusion region sequence is recognized by HLA-DR2a restricted cytotoxic T lymphocytes and presented by HLA-DR matched cells transfected with an Iib2a2 construct. Blood. 1999;94:1038–1045
- Maslak PJ, Dao T, Gomez M, et al. A pilot vaccination trial of synthetic analog peptides derived from BCR-ABL breakpoints in CML patients with minimal disease. Leukemia, Feb 7, 2008 [Epub].
- Lonafarnib reduces the resistance of primitive quiescent CML cells to imatinib mesylate in vitro. Leukemia. 2005;9:1184–1191
- . Evolving molecular therapy for chronic myeloid leukemia – are we on target?. Hematology. 2005;10:349–359
- Wilms' tumor gene 1 (WT1) in human neoplasia. Leukemia. 2005;19:1318–1323
- . Expression of Wilms' tumor gene (WT1) in human leukemias. Leukemia. 1992;6:405–409
- WT1-specific serum antibodies in patients with leukemia. Clinical Cancer Research. 2001;7(Suppl. 3):761s–765s
- . WT1 in acute leukemia, chronic myelogenous leukemia and myelodysplastic syndrom: therapeutic potential of WT1 targetted therapies. Leukemia. 2003;17:1301–1312
- Immunotherapeutic targeting of Wilms' tumor protein. Current Opinion in Molecular Therapeutics. 2007;9:62–69
- Cancer immunotherapy targeting Wilms tumor gene WT1 product. Journal of immunology (Baltimore, Md.: 1950). 2000;164:1873–1880
- Defining MHC class II T helper epitopes from WT1 antigen. Cancer Immunology Immunotherapy. 2006;55:850–860
- Prediction of an HLA-DR-binding peptide derived from Wilms' tumor 1 protein and demonstration of in vitro immunogenicity of WT1 (124-138)-pulsed dendritic cells generated according to an optimal protocol. Cancer Immunology Immunotherapy. 2002;51:271–281
- Identification and characterization of a WT1 (Wilms tumor gene) protein-derived HLA-DRB1*0405-restricted 16-mer helper peptide that promotes the induction and activation of WT1-specific cytotoxic T lymphocytes. Journal of Immunotherapy. 2007;30:282–293
- Direct recognition and lysis of leukemia cells by WT1-specific CD4+ T lymphocytes in an HLA class II-restricted manner. Blood. 2005;106:1415–1418
- Peptide epitopes from the Wilms tumor 1 oncoprotein stimulate CD4+ and CD8+ T cells that recognize and kill human malignant mesothelioma tumor cells. Clinical Cancer Research. 2007;13:4547–4555
- Wilms tume gene peptide-based immunotherapy for patients with overt leukemia from myelodysplastic syndrome (MDS) or MDS with myelofibrosis. International Journal of Hematology. 2003;78:56–61
- Tsuboi A, Oka Y, Nakajima H, et al. Long-term follow-up of three patients with acute myeloid leukemia with minimal residual disease who were treated with WT1 vaccination. In: Third international conference on WT1 in human malignancies, Berlin Sept 20-21, 2007.
- Two distinct HLA-A0201-presented epitopes of the Wilms tumor antigen 1 can function as targets for leukemia-reactive CTL. Blood. 2002;100:3835–3837
- WT1(235), a ninemer peptide derived from Wilms tumor gene product, is a candidate peptide for the vaccination of HLA-A0201-positive patients with hematopoietic malignancies. International Journal of Hematology. 2005;82:458–459
- Leukemia-associated antigen specific T-cell responses following combined PR1 and WT1 peptide vaccination in patients with myeloid malignancies. Blood. 2008;111:236–242
- Improved human T-cell responses against synthetic HLA-A0201 analog peptides derived from the WT1 oncoprotein. Leukemia. 2006;20:2025–2033
- Krug LM, Maslak P, Dao T, et al Clinical development of a heteroclitic WT-1 peptide vaccine in patients with hematologic and thoracic malignancies. In: Third international conference on WT1 in human malignancies, Berlin Sept. 20-21, 2007.
- Identification of a highly immunogenic HLA-A*01-binding T cell epitope of WT1. Clinical Cancer Research. 2006;12:7476–7482
- . Neutrophil granule proteins as targets of leukemia-specific immune responses. Current Opinion in Hematology. 2006;13:15–20
- Induction of granulocytic differentiation by 2 pathways. Blood. 2002;99:4406–4412
- Cytotoxic lymphocytes specific for a nonpolymorphic proteinase 3 peptide preferentially inhibit chronic myeloid leukemia colony-forming units. Blood. 1997;90:2529–2534
- A PR1 human leukocyte antigen-A2 tetramer can be used to isolate low-frequency cytotoxic T lymphocytes from healthy donors that selectively lyse chronic myelogenous leukemia. Cancer Research. 1999;59:2675–2681
- Chronic myelogenous leukemia shapes host immunity by selective deletion of high-avidity leukemia-specific T cells. The Journal of Clinical Investigation. 2003;111:639–674
- Evidence that specific T lymphocytes may participate in elimination of chronic myelogenous leukemia. Natural Medicines. 2000;6:1018–1023
- Identification and characterization of epitopes of the receptor for hyaluronic acid-mediated motility (RHAMM/CD168) recognized by CD8+ T cells of HLA-A2-positive patients with acute myeloid leukemia. Blood. 2005;106:938–945
- . Combining cancer vaccines with chemotherapy. Expert Opinion. 2005;6:2813–2820
- Inhibition of suppressor-cell activity by cyclophosphamide in patients with malignant melanoma. Journal of Biological Response Modifiers. 1987;6:392–403
- Adoptive transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. Journal of Clinical Oncology. 2005;23:2346–2357
- Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy. Oncogene. 2005;24:5226–5234
PII: S1521-6926(08)00051-0
doi: 10.1016/j.beha.2008.05.001
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Best Practice & Research Clinical Haematology
Volume 21, Issue 3
, Pages 391-404
, September 2008
