Best Practice & Research Clinical Haematology
Volume 21, Issue 1 , Pages 79-83 , March 2008

Should all unrelated donors for transplantation be matched?

  • Daniel Weisdorf, MD (Professor of Medicine, Director)

      Affiliations

    • Corresponding Author InformationTel.: +1 612 624 3101; Fax: +1 612 625 6919.

References 

  1. Petersdorf EW, Longton GM, Anasetti C, et al. The significance of HLA-DRB1 matching on clinical outcome after HLA-A, B, DR identical unrelated donor marrow transplantation. Blood. 1995;86:1606–1613
  2. Petersdorf EW, Gooley TA, Anasetti C, et al. Optimizing outcome after unrelated marrow transplantation by comprehensive matching of HLA class I and II alleles in the donor and recipient. Blood. 1998;92:3515–3520
  3. Petersdorf EW, Hansen JA, Martin PJ, et al. Major-histocompatibility-complex class I alleles and antigens in hematopoietic-cell transplantation. The New England Journal of Medicine. 2001;345:1794–1800
  4. Sasazuki T, Juji T, Morishima Y, et al. Effect of matching of class I HLA alleles on clinical outcome after transplantation of hematopoietic stem cells from an unrelated donor. Japan Marrow Donor Program. The New England Journal of Medicine. 1998;339:1177–1185
  5. Morishima Y, Sasazuki T, Inoko H, et al. The clinical significance of human leukocyte antigen (HLA) allele compatibility in patients receiving a marrow transplant from serologically HLA-A, HLA-B, and HLA-DR matched unrelated donors. Blood. 2002;99:4200–4206
  6. Flomenberg N, Baxter-Lowe LA, Confer D, et al. Impact of HLA class I and class II high resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplant outcome. Blood. 2004;104:1923–1930
  7. Tiercy JM, Passweg J, van BA, et al. Isolated HLA-C mismatches in unrelated donor transplantation for CML. Bone Marrow Transplantation. 2004;34:249–255
  8. Greinix HT, Fae I, Schneider B, et al. Impact of HLA class I high-resolution mismatches on chronic graft-versus-host disease and survival of patients given hematopoietic stem cell grafts from unrelated donors. Bone Marrow Transplantation. 2005;35:57–62
  9. Shaw BE, Marsh SG, Mayor NP, et al. HLA-DPB1 matching status has significant implications for recipients of unrelated donor stem cell transplants. Blood. 2006;107:1220–1226
  10. Lee SJ, Klein J, Haagenson M, et al. High resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation. Blood. 2007;110:4576–4583

PII: S1521-6926(07)00101-6

doi: 10.1016/j.beha.2007.11.011

Best Practice & Research Clinical Haematology
Volume 21, Issue 1 , Pages 79-83 , March 2008

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