Best Practice & Research Clinical Haematology
Volume 20, Issue 3 , Pages 367-384 , September 2007

Differential diagnosis in chronic lymphocytic leukaemia

  • Estella Matutes, MD, PhD, FRCPath (Reader and Consultant Haematologist)

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +44 207 8082609; Fax: +44 208 7224221.

References 

  1. Cheson BD, Bennet JM, Grever M, et al. National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood. 1996;87:4990–4997
  2. In:  Jaffe ES,  Harris NL,  Stein H,  Vardiman JW editor. World Health Organization classification of tumours. Pathology and genetics of tumours of haematopoietic and lymphoid tissues. Lyon: IARC Press; 2001;
  3. Marti GE, Rawstron AC, Ghia P, et al. The International Familial CLL Consortium. Diagnostic criteria for monoclonal B-cell lymphocytosis. British Journal of Haematology. 2005;130:325–332
  4. Rawstron AC, Bennett JM, Fuller J, et al. Inherited predisposition to CLL is detectable as subclinical monoclonal B-lymphocyte expansion. Blood. 2002;100:2289–2290
  5. Bennet JM, Catovsky D, Daniel MT, et al. The French–American–British (FAB) Cooperative group. Proposals for the classification of chronic (mature) B and T lymphoid leukemias. Journal of Clinical Pathology. 1989;42:567–584
  6. Matutes E, Oscier D, Garcia Marco J, et al. Trisomy 12 defines a group of CLL with atypical morphology. Correlation between cytogenetic, clinical and laboratory features in 544 patients. British Journal of Haematology. 1996;92:382–388
  7. Matutes E, Polliack A. Morphological and immunophenotypic features of chronic lymphocytic leukaemia. Reviews in Clinical and Experimental Hematology. 2000;4:22–47
  8. Enno A, Catovsky D, O'Brien M, et al. ‘Prolymphocytoid’ transformation of chronic lymphocytic leukaemia. British Journal of Haematology. 1979;41:9–18
  9. Melo JV, Catovsky D, Galton DAG. The relationship between chronic lymphocytic leukaemia and prolymphocytic leukaemia. I. Clinical and laboratory features of 300 patients and characterization of an intermediate group. British Journal of Haematology. 1986;63:377–387
  10. Cordone I, Matutes E, Catovsky D. Monoclonal antibody Ki-67 identifies B and T cells in cycle in chronic lymphocytic leukemia: correlation with disease activity. Leukemia. 1992;6:902–906
  11. Oscier D, Matutes E, Copplestone A, et al. Atypical morphology: an adverse prognostic factor for disease progression in stage A CLL independent of trisomy 12. British Journal of Haematology. 1997;98:934–939
  12. Criel A, Wlodarska I, Meeus P, et al. Trisomy 12 is uncommon in typical chronic lymphocytic leukaemia. British Journal of Haematology. 1994;87:523–528
  13. Hamblin TJ, Davis Z, Gardiner A, et al. Unmutated immunoglobulin VH genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood. 1999;94:1848–1854
  14. Thornton PD, Bellas C, Santon A, et al. Richter's transformation of chronic lymphocytic leukemia. The role of fludarabine and the Epstein–Barr virus in its pathogenesis. Leukemia Research. 2005;29:389–395
  15. Caligaris-Cappio F. B-chronic lymphocytic leukemia: a malignancy of anti-self B cells. Blood. 1996;87:2615–2620
  16. Matutes E, Owusu-Ankomah K, Morilla R, et al. The immunological profile of B-cell disorders and proposal of a scoring system for the diagnosis of CLL. Leukemia. 1994;8:1640–1645
  17. Moreau EJ, Matutes E, A'Hern RP, et al. Improvement of the chronic lymphocytic leukemia scoring system with monoclonal antibody SN8 (CD79b). American Journal of Clinical Pathology. 1997;108:378–382
  18. Contos MJ, Kornstein MJ, Innes DJ, Bben-Ezra J. The utility of CD20 and CD43 in subclassification of low-grade B-cell lymphoma on paraffin sections. Modern Pathology. 1992;5:631–633
  19. Jung G, Eisenmmann JC, Thiebault S, Henon P. Cell surface CD43 determination improves diagnostic precision in late B-cell diseases. British Journal of Haematology. 2003;120:496–499
  20. Delgado J, Matutes E, Morilla AM. Diagnostic significance of CD20 and FMC7 expression in B-cell disorders. American Journal of Clinical Pathology. 2003;120:754–759
  21. Damle RN, Wasil T, Fais F, et al. Immunoglobulin V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood. 1999;94:1840–1847
  22. Crespo M, Bosch F, Villamor N, et al. ZAP-70 expression as a surrogate for Immunoglobulin variable region mutations in chronic lymphocytic leukemia. The New England Journal of Medicine. 2003;348:1764–1775
  23. Ibrahim S, Keating M, Do K-A, et al. CD38 expression as an important prognostic factor in B-cell chronic lymphocytic leukemia. Blood. 2001;98:181–186
  24. Ben Ezra J, Burke JS, Swartz WG, et al. Small lymphocytic lymphoma: a clinicopathologic analysis of 268 cases. Blood. 1989;73:579–587
  25. Lampert IA, Wotherspoon A, Van Noorden S, Hasserjian RP. High expression of CD23 in the proliferation centers of chronic lymphocytic leukaemia in lymph nodes and spleen. Human Pathology. 1999;30:648–654
  26. Dohner H, Stilgenbauer S, Benner A, et al. Genomic aberrations and survival in chronic lymphocytic leukemia. The New England journal of medicine. 2000;343:1910–1916
  27. Matutes E, Carrara P, Coignet L, et al. FISH analysis for BCL-1 rearrangements and trisomy 12 helps the diagnosis of atypical B cell leukaemias. Leukemia. 1999;13:1721–1726
  28. Brito-Babapulle V, Ellis J, Matutes E, et al. Translocation t(11;14)(q13;q32) in chronic lymphoid disorders. Genes, Chromosomes and Cancer. 1992;5:158–165
  29. Cuneo A, Bigoni R, Negrini M, et al. Cytogenetic and interphase cytogenetic characterisation of atypical chronic lymphocytic leukemia carrying bcl-1 translocation. Cancer Research. 1997;57:1144–1150
  30. Michaux L, Dierlamm J, Wlodarska I, et al. t(14;19)/BCL3 rearrangements in lymphoproliferative disorders: a review of 23 cases. Cancer Genetics and Cytogenetics. 1997;94:36–43
  31. Huh YO, Abruzzo LV, Rassidakis GZ, et al. The t(11;14)(q32;q13) in B-cell leukemia: a clinicopathologic and cytogenetic study of seven cases best classified as atypical lymphoid leukaemia. British Journal of Haematology. 2007;136:220–228
  32. Klein U, Tu Y, Stolovitzky GA, et al. Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory cells. The Journal of Experimental Medicine. 2001;194:1625–1638
  33. Ruchlemer R, Parry-Jones N, Brito-Babapulle V, et al. B-Prolymphocytic leukaemia with t(11;14) revisited: a splenomegalic form of mantle cell lymphoma evolving with leukaemia. British Journal of Haematology. 2004;125:330–336
  34. Lens D, Matutes E, Catovsky D, Coignet LJA. Frequent deletions at 11q23 and 13q14 in B-cell prolymphocytic leukemia (B-PLL). Leukemia. 2000;14:427–430
  35. Lens D, de Schouwer PJ, Hamoudi RA, et al. P53 abnormalities in B-cell prolymphocytic leukemia. Blood. 1997;89:2015–2023

PII: S1521-6926(07)00022-9

doi: 10.1016/j.beha.2007.03.001

Best Practice & Research Clinical Haematology
Volume 20, Issue 3 , Pages 367-384 , September 2007

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