Best Practice & Research Clinical Haematology
Volume 20, Issue 1 , Pages 13-18 , March 2007

The leukemic stem cell

  • Craig T. Jordan (Associate Professor of Medicine)

      Affiliations

    • Corresponding Author InformationTel.: +1 585 275 6339; Fax: +1 708 575 3785.

References 

  1. Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nature Medicine. 1997;3:730–737
  2. Gilliland DG, Jordan CT, Felix CA. The molecular basis of leukemia. Hematology/The Education Program of the American Society of Hematology. 2004;80–97
  3. Tallman MS, Gilliland DG, Rowe JM. Drug therapy for acute myeloid leukemia. Blood. 2005;106:1154–1163
  4. Tallman MS. New strategies for the treatment of acute myeloid leukemia including antibodies and other novel agents. Hematology/The Education Program of the American Society of Hematology. 2005;143–150
  5. Kantarjian HM, Estey EH, Keating MA. New chemotherapeutic agents in acute myeloid leukemia. Leukemia. 1996;10(supplement 1):S4–S6
  6. Li TK, Houghton PJ, Desai SD, et al. Characterization of ARC-111 as a novel topoisomerase I-targeting anticancer drug. Cancer Research. 2003;63:8400–8407
  7. Deininger MW, Druker BJ. Specific targeted therapy of chronic myelogenous leukemia with imatinib. Pharmacological Reviews. 2003;55:401–423
  8. Smith BD, Levis M, Beran M, et al. Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia. Blood. 2004;103:3669–3676
  9. Xu Q, Simpson SE, Scialla TJ, et al. Survival of acute myeloid leukemia cells requires PI3 kinase activation. Blood. 2003;102:972–980
  10. Guzman ML, Swiderski CF, Howard DS, et al. Preferential induction of apoptosis for primary human leukemic stem cells. Proceedings of the National Academy of Sciences of the USA. 2002;99:16220–16225
  11. Guzman ML, Rossi RM, Karnischky L, et al. The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells. Blood. 2005;105:4163–4169

PII: S1521-6926(06)00074-0

doi: 10.1016/j.beha.2006.10.005

Best Practice & Research Clinical Haematology
Volume 20, Issue 1 , Pages 13-18 , March 2007

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