Best Practice & Research Clinical Haematology
Volume 20, Issue 2 , Pages 209-217, June 2007

Risk assessment in haematopoietic stem cell transplantation: Viral status

  • Per Ljungman, MD, PhD (Professor, Head)

      Affiliations

    • Corresponding Author InformationTel.: +46 8 58582507; Fax: +46 8 7748725.

Hematology Center, Karolinska University Hospital, Karolinska Institute, SE-14186 Stockholm, Sweden

Viral infections have been important complications in the transplant procedure from the early days of stem-cell transplantation, causing significant morbidity and mortality. It is important for the management of patients to assess the risk for viral infections that might develop after the stem-cell transplantation. This can be exemplified by cytomegalovirus (CMV) and other herpesviruses, but risk assessment is also important for other viral infections. The aim of this review is to describe current knowledge regarding recipient and donor serological status for viral infections.

Key words: viral infections, serology, CMV, stem-cell transplantation, donors

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PII: S1521-6926(06)00063-6

doi:10.1016/j.beha.2006.09.003

Best Practice & Research Clinical Haematology
Volume 20, Issue 2 , Pages 209-217, June 2007