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Best Practice & Research Clinical Haematology
Volume 19, Issue 2
, Pages 263-268
, June 2006
Genomic approaches in acute leukemia
References
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- MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia. Nat Genet. 2002;30:41–47
- Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell. 2002;1:133–143
- Gene expression profiling of pediatric acute myelogenous leukemia. Blood. 2004;104:3679–3687
- Acute myeloid leukemias with reciprocal rearrangements can be distinguished by specific gene expression profiles. Proc Natl Acad Sci USA. 2002;99:10008–10013
- Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia. N Engl J Med. 2004;350:1605–1616
- Prognostically useful gene-expression profiles in acute myeloid leukemia. N Engl J Med. 2004;350:1617–1628
- Inhibition of FLT3 in MLL. validation of a therapeutic target identified by gene expression based classification. Cancer Cell. 2003;3:173–183
- FLT3 mutations in childhood acute lymphoblastic leukemia. Blood. 2004;103:3544–3546
- Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412. Blood. 2005;105:54–60
- A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease. Blood. 2005;105:986–993
- Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia. Blood. 2004;103:3669–3676
- Effects of SU5416, a small molecule tyrosine kinase receptor inhibitor, on FLT3 expression and phosphorylation in patients with refractory acute myeloid leukemia. Leuk Res. 2004;28:679–689
- Gene expression-based high-throughput screening (GE-HTS) and application to leukemia differentiation. Nat Genet. 2004;36:257–263
PII: S1521-6926(05)00103-9
doi: 10.1016/j.beha.2005.11.001
© 2005 Elsevier Ltd. All rights reserved.
« Previous
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Best Practice & Research Clinical Haematology
Volume 19, Issue 2
, Pages 263-268
, June 2006
